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Goa, India

Our efforts are supported by a large and expanding PR&D and scale-up team in Goa, India.

Located in North Goa, our Santa Monica Works facility was one of the first and largest industrial locations in Goa.

The site is certified for ISO9001:2015, 14001:2015, 45001:2018 & ISO50001 and has successfully completed Together for Sustainability (TfS) audit with a score of 100/100. The site has also obtained “Responsible Care” certification from the Indian Chemical Council and is NABL accredited.

Since 5 years the site operates a biomass plant to generate utilities for the site making it a more sustainable operation.

The R&D building has 7 Laboratories with a total 58 fume hoods. The current strength of the department is in excess of 90 professionals & team leaders having Ph.D and vast international work experience. We operate mostly with jacketed reactors from 0.5 up to 20L scale which enables development of robust processes ready for tech transfer.

Our Analytical Development Department:

  • Analytical method development
  • Method verification and validation
  • 5 batch analysis under GLP conditions (planned and monitored by Deccan via third party)
  • Cross-contamination analysis
  • Analytical support for process development
  • Analytical support for alternate vendor development
  • Identification and characterization of impurities
  • Waste characterization
Goa Deccan Site

Our Goa site has a pilot plant reactor capacities ranging from 100 Lt – 1600 Lt

  • Material of Construction in Hastelloy C-22 and Glass lined reactors to handle corrosive chemicals
  • Therminol Indirect heating cooling for reactors and condensers
  • Capable to handle pressure reactions, gas addition etc.
  • DCS controlled operation
  • Bridging station network for multiple transfers
  • Possibility of carrying out reactions at very varied temperatures of -70 to + 170°C. with addition of powder, gas or liquid, hydrogenation reactions.

Process Safety Assessment

All chemical processes are assessed for process hazards (Chemical reaction hazards and Fire & Explosion hazards associated with powders) before scale-up. Chemical reaction hazards are assessed at the Process Hazards Lab at our Goa T&E centre. Fire & explosion hazards associated with powders are currently assessed at an external testing laboratory.

The assessment for chemical reaction hazards starts at the early stage with close coordination between the process chemistry and the process hazards team, where the inherent hazards are identified using literature screening and chemical reactivity worksheets. This helps in identifying any show-stoppers/potential incidents at the lab scale during the very early stage of process development.

This is followed by experimentation with calorimeters.

  • Mettler Toledo Differential scanning calorimetry (DSC) with High-Pressure gold plated crucibles and Carius tube testing is used for initial screening for heat and gas generation from thermal instabilities.
  • This is followed by Accelerating Rate Calorimetry (ARC) and ambient pressure Dewar calorimetry for studying the sample under low heat loss (adiabatic) conditions. Isothermal measurements are also carried out using the DSC and ARC for assessing auto-catalytic thermal decompositions.
  • Reaction calorimeter (RC1e) along with the U-tube gas manometer is used for studying heat of reaction, gas generation and kinetics for synthesis reactions operating from ambient pressure to 6barg pressure.

The lab is managed by a team of chemical engineers and physical chemists who have the necessary expertise. The experience of the team members ranges from 14yrs to 7yrs in Process hazard assessments with previous assignments in global reputed pharmaceutical and agrochemical companies like AstraZeneca and Syngenta. More than 200 assessments have been carried out in the last 7yrs for complex chemistries like nitration, oxidation, grignard, chloro-oxidations, diazotisation etc.

The results from the hazard assessment is used to arrive at the “Basis of Safety” and this is reported in the form of Chemical Reaction Hazard Assessment report. The process is then risk assessed by the Process Risk Assessment team to evaluate the layers of protection before scale-up at pilot and commercial scales.

The process hazards assessment lab also supports the management of change system to assess the risk associated with the proposed process changes.

Primopus Process Safety Assessment at Goa

Maintaining Biodiversity and the Ecological Balance

The facilities was designed and built to co-exist in harmony. It is home to two Lakes -water harvesting (for 40 years)

Flora

More than 87 different species of trees, shrubs, herbs, creepers and grasses.

Animals

More than 50 species of birds including Cormorants, Herons, Storks, Ibis, Geese, Eagles. The site also is home to a variety of mammals and reptiles living in harmony.

Goa site in India | Primopus